The association of vitamin D and vitamin E levels at birth with bronchopulmonary dysplasia in preterm infants.

摘要: Background Despite improvements made in neonatal care, bronchopulmonary dysplasia (BPD) is still the most common respiratory disease preterm infants. The relationship between blood contents of vitamin D/E premature infants and BPD controversial. Methods Preterm were recruited as research subjects. On basis inclusion exclusion criteria, a total 133 eligible cases finally included. A 63 with clear diagnosis 5 who died before case group, 65 non-BPD equivalent baseline characteristics control group. group included 38 Grade Ⅰ, 18 Ⅱ, 12 Ⅲ. D E cord different groups detected by high-performance liquid chromatography enzyme-linked immunosorbent assay. Correlation analysis adopted Pearson correlation analytic method. Results serum levels at birth remarkably lower than both which also correlated severity BPD. negatively oxygen support duration required for Conclusion This study deepens our understanding field pathogenesis demonstrating an association deficiency severity, suggesting that might have potential clinical value prognosis treatment