Chemotherapy of Nematode Infections of Veterinary Importance, with Special Reference to Drug Resistance

摘要: Publisher Summary The historical succession of one drug class after another has resulted in part from sequential improvement characteristics (spectrum, safety, convenience), but also the emergence resistance. phenomenon resistance, so characteristic treatment infectious diseases general, is a prominent feature new era antinematodal therapy. Anthelmintic use may vary to some extent various parts world, it rests largely on common set chemical compounds. An aspect older drugs development delivery technology. Administration injectable product gives high efficacy against many nematode and arthropod parasites, these are disucssed chapter. active gastrointestinal pulmonary nematodes, immature as well mature worms, inhibited fourth-stage larvae. susceptible arthropods include ticks, lice, mites, grubs. Drug resistance heritable reduction sensitivity parasite population action drug, being expressed decrease frequency individual parasites affected by exposure drug. generally results decreased uptake, increased metabolism or changes at drug-receptor site.