Predictors of Positive Radial Margin Status in a Population Based Cohort of Patients with Rectal Cancer
作者： P Terry Phang , Hagen Kennecke , Colleen E McGahan , John MacFarlane , Greg McGregor
DOI: 10.3747/CO.V15I2.245
关键词:
摘要: Background: Surgical margin status is an important predictor of risk relapse among patients with rectal cancer. Methods: Patients referred to the British Columbia Cancer Agency for consideration adjuvant therapy adenocarcinoma were included. Predictors positivity determined from uni-and multivariate analysis. Results: Of 340 patients, 83% had negative resection margins. In 268 resectable tumors, a significantly higher rate was observed in low tumors (32.2%), compared mid (3.9%) and high (14.3%) tumors. Among 59 locally advanced cancer treated pre-operative radiation (+/- chemotherapy), 32% those 50% (11/22) T4 positive margin. Conclusions: population cohort, distal third location, presentation, cancers represent subgroups where further improvement required.
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