Endectocide activity of a new long-action formulation containing 2.25% ivermectin+1.25% abamectin in cattle.

摘要: The present work aimed to evaluate the endectocide activity of a new injectable long-action formulation, containing ivermectin (IVM) and abamectin (ABA). In each one four experiments performed, following groups were formed: group I: 2.25% IVM (450 mg/kg) + 1.25% ABA (250 mg/kg), II: 3.15% (630 III: control. Eighteen bovine naturally infected by gastrointestinal nematoda selected for anthelmintic evaluation necropsied on posttreatment day (PTD) 14 estimate total parasitic burden. For Rhipicephalus (Boophilus) microplus field trial, 30 means counts semi-engorged R.(B.) microplusand therapeutic residual efficacy evaluated tick PTDs 1, 3, 7, 14, 21, 28, 35, 42, 49, 56, 63, 70, 77, 84 91. stall test, 15 calves artificially infested with 5000 R. (B.) (Mozzo strain) larvae three times week daily collections all engorged female ticks detached from calf performed until PTD80. Forty Dermatobia hominislarvaewere numberof larvaewas counted visual tactile inspection 91 105. this formulation 1% doramectin (200 was also used. eliminated eight species nematode identified. avermectins association against Haemonchus placei, Cooperia spatulata C. punctata 89.64%, 98.84% 97.69%, while achieved 30.98%, 84.79% 75.56%, respectively. two formulations showed reduced acaricide action PTD 1 reaching high percentages onward. above 95% in period between 21 49. it observed no difference (P > 0.05) regarding during entire period. number 77 D. hominis prevented parasite reestablishment These results indicate that higher