Metallo-ß-lactamases: a review.

作者: Payam Behzadi , Herney Andrés García-Perdomo , Tomasz M. Karpiński , Lernik Issakhanian

DOI: 10.1007/S11033-020-05651-9

关键词:

摘要: Microbial pathogens including Enterobacteriaceae family members bear different antibiotic resistance genes comprising Extended-Spectrum-s-Lactamases (ESBLs) and Metallo-s-Lactamases (MBLs) on their chromosomes mobile genetic elements such as plasmids transposons. Because of the clinical concern regarding MBLs in global public healthcare system, this review focuses characteristics MBLs. For preparing article, databases, websites search engines MEDLINE, SCOPUS, SCIENCEDIRECT GOOGLE SCHOLAR were searched via MeSH keywords Enterobacteriaceae, Escherichia coli, Klebsiella pneumoniae, MBL Bioinformatics. Different types papers articles original which published between years 1980 2020 searched, studied selected by authors. The results show that, importance spread among microbial may lead to progressive studies for definite treatment. use computational biology chemistry bioinformatics has had effective consequences recognition identification properties application bioinformatic software tools databases gives us a great promise production inhibitors against have

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