A Bio-Hybrid Tactile Sensor Incorporating Living Artificial Skin and an Impedance Sensing Array
作者： David Cheneler , Elisa Buselli , Domenico Camboni , Carl Anthony , Liam Grover
DOI: 10.3390/S141223781
关键词:
摘要: The development of a bio-hybrid tactile sensor array that incorporates skin analogue comprised alginate encapsulated fibroblasts is described. electrical properties are modulated by mechanical stress induced during contact, and changes detected ten-channel dual-electrode impedance sensing array. By continuously monitoring the at fixed frequency, whilst normal tangential loads applied to surface, transient mechanotransduction has been observed. results demonstrate effectiveness feasibility preliminary prototype sensor.
mdpi.com
core.ac.uk
doaj.org参考文章(48)
M E Wall, A J Banes, Early responses to mechanical load in tendon: role for calcium signaling, gap junctions and intercellular communication. Journal of Musculoskeletal & Neuronal Interactions. ,vol. 5, pp. 70- 84 ,(2005)
Nicola Claire Hunt, An alginate hydrogel matrix for the localised delivery of a fibroblast/ keratinocyte co-culture to expedite wound healing University of Birmingham. ,(2010)
Georgina Kaklamani, Calogero Oddo, David Cheneler, Liam Grover, Eliza Buselli, C. Carrozza, Lucia Beccai, Bio-hybrid tactile sensor and experimental set-up for investigating and mimicking the human sense of touch ,(2012)
Nicholas Wettels, Jeremy A. Fishel, Gerald E. Loeb, Multimodal Tactile Sensor The Human Hand as an Inspiration for Robot Hand Development. pp. 405- 429 ,(2014) , 10.1007/978-3-319-03017-3_19
E N Unemori, E P Amento, Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts. Journal of Biological Chemistry. ,vol. 265, pp. 10681- 10685 ,(1990) , 10.1016/S0021-9258(18)87000-4
A S Narayanan, R C Page, J Swanson, Collagen synthesis by human fibroblasts. Regulation by transforming growth factor-β in the presence of other inflammatory mediators Biochemical Journal. ,vol. 260, pp. 463- 469 ,(1989) , 10.1042/BJ2600463
Olav Smidsrød, Molecular basis for some physical properties of alginates in the gel state Faraday Discussions of The Chemical Society. ,vol. 57, pp. 263- 274 ,(1974) , 10.1039/DC9745700263
Jon A. Rowley, Gerard Madlambayan, David J. Mooney, Alginate hydrogels as synthetic extracellular matrix materials Biomaterials. ,vol. 20, pp. 45- 53 ,(1999) , 10.1016/S0142-9612(98)00107-0
Nicola C. Hunt, Liam M. Grover, Cell encapsulation using biopolymer gels for regenerative medicine Biotechnology Letters. ,vol. 32, pp. 733- 742 ,(2010) , 10.1007/S10529-010-0221-0
W.Y. Gu, H. Yao, C.Y. Huang, H.S. Cheung, New insight into deformation-dependent hydraulic permeability of gels and cartilage, and dynamic behavior of agarose gels in confined compression. Journal of Biomechanics. ,vol. 36, pp. 593- 598 ,(2003) , 10.1016/S0021-9290(02)00437-2