Molecular and Immunohistochemical Markers of Diagnostic and Prognostic Value in Testicular Tumors

摘要: Primary testicular tumors are rare and the great majority fall into one of two major categories: germ cell sex cord-stromal tumors. Germ (GCTs) most common, but histogenesis, morphology, genotypic features vary greatly depending on whether they develop in a prepubertal gonad or an adult. While there is little debate histogenesis molecular characteristics adult onset GCTs, markers associated with drug resistance poor prognosis have yet to be defined. Surgery remains key effective treatment since systemic therapies remain elusive; very known regarding mechanisms this disease. The types cells many, judicious use immunohistochemical can useful adjunct arrive at correct diagnosis.