Human insulin: much ado about hypoglycaemia (un)awareness.

摘要: The biological effects, hypoglycaemic symptoms, endocrine counterregulatory responses and glucose recovery following the injection of purified porcine human insulin preparations were compared in a number controlled clinical investigations prospective trials. In these studies involving healthy volunteers, Type 1 (insulin-dependent) diabetic patients on continuous subcutaneous infusion or intensified conventional therapy treated 2 (non-insulin-dependent) patients, no differences with regard to responses, awareness long-term incidence severe hypoglycaemia between identified. These data fail confirm any specific risk attributable use treatment diabetes mellitus.