Impaired peripheral vasodilation during graded systemic hypoxia in healthy older adults: role of the sympathoadrenal system.

作者: Jennifer C. Richards , Anne R. Crecelius , Dennis G. Larson , Gary J. Luckasen , Frank A. Dinenno

DOI: 10.1152/AJPHEART.00794.2016

关键词:

摘要: We found that the lack of peripheral vasodilation during graded systemic hypoxia with aging is not mediated by sympathoadrenal system, strongly implicating local vascular control mechanisms in ...

参考文章(58)
Darren P. Casey, Brandon D. Madery, Tasha L. Pike, John H. Eisenach, Niki M. Dietz, Michael J. Joyner, Brad W. Wilkins, Adenosine receptor antagonist and augmented vasodilation during hypoxic exercise Journal of Applied Physiology. ,vol. 107, pp. 1128- 1137 ,(2009) , 10.1152/JAPPLPHYSIOL.00609.2009
Kevin P. Davy, Douglas R. Seals, Hirofumi Tanaka, Augmented Cardiopulmonary and Integrative Sympathetic Baroreflexes but Attenuated Peripheral Vasoconstriction With Age Hypertension. ,vol. 32, pp. 298- 304 ,(1998) , 10.1161/01.HYP.32.2.298
Frank A. Dinenno, Hirofumi Tanaka, Brian L. Stauffer, Douglas R. Seals, Reductions in basal limb blood flow and vascular conductance with human ageing: role for augmented α-adrenergic vasoconstriction The Journal of Physiology. ,vol. 536, pp. 977- 983 ,(2001) , 10.1111/J.1469-7793.2001.00977.X
Andrew E. Beaudin, Julien V. Brugniaux, Matthias Vöhringer, Jacqueline Flewitt, Jordin D. Green, Matthias G. Friedrich, Marc J. Poulin, Cerebral and myocardial blood flow responses to hypercapnia and hypoxia in humans. American Journal of Physiology-heart and Circulatory Physiology. ,vol. 301, ,(2011) , 10.1152/AJPHEART.00281.2011
W.Wayne Lautt, Resistance or conductance for expression of arterial vascular tone. Microvascular Research. ,vol. 37, pp. 230- 236 ,(1989) , 10.1016/0026-2862(89)90040-X
Frank A. Dinenno, Pamela P. Jones, Douglas R. Seals, Hirofumi Tanaka, Limb Blood Flow and Vascular Conductance Are Reduced With Age in Healthy Humans Circulation. ,vol. 100, pp. 164- 170 ,(1999) , 10.1161/01.CIR.100.2.164
Frank A. Dinenno, Niki M. Dietz, Michael J. Joyner, Aging and Forearm Postjunctional α-Adrenergic Vasoconstriction in Healthy Men Circulation. ,vol. 106, pp. 1349- 1354 ,(2002) , 10.1161/01.CIR.0000028819.64790.BE
David W. Richardson, Hermes A. Kontos, A. Jarrell Raper, John L. Patterson, Modification by Beta-Adrenergic Blockade of the Circulatory Responses to Acute Hypoxia in Man* Journal of Clinical Investigation. ,vol. 46, pp. 77- 85 ,(1967) , 10.1172/JCI105513
Stefano Taddei, Agostino Virdis, Lorenzo Ghiadoni, Guido Salvetti, Giampaolo Bernini, Armando Magagna, Antonio Salvetti, Age-Related Reduction of NO Availability and Oxidative Stress in Humans Hypertension. ,vol. 38, pp. 274- 279 ,(2001) , 10.1161/01.HYP.38.2.274
Anne R. Crecelius, Brett S. Kirby, Jennifer C. Richards, Leora J. Garcia, Wyatt F. Voyles, Dennis G. Larson, Gary J. Luckasen, Frank A. Dinenno, Mechanisms of ATP-mediated vasodilation in humans: modest role for nitric oxide and vasodilating prostaglandins. American Journal of Physiology-heart and Circulatory Physiology. ,vol. 301, ,(2011) , 10.1152/AJPHEART.00469.2011