Deficient cellular immunity in endometriosis

摘要: Abstract Cell-mediated autoimmune responses were studied by means of in vivo and vitro techniques five rhesus monkeys with spontaneous endometriosis. The results compared similar data obtained from normal without studies included intrademal injection autologous antigens prepared uterine endometrium, ectopic or peritoneum, the mitogen, phytohemagglutinin (PHA). Skin biopsies at 48 hours evaluated under light microscope for perivascular lymphocytic infiltration. mean number lymphocytes per high-power field after endometrial antigen was significantly smaller animals affected endometriosis than control group. There no significant difference response to peritoneal between groups. Animals both groups responded readily PHA marked Lymphocyte stimulation same assays micro-methods. group less groups, all this study indicate that have an altered cellular immune antigens. Although immunologically competent, as judged PHA, indicated a decrease cell-mediated These suggest cells translocated their location may implant only women specific alteration immunity. New is thus shed on cause