The Photobiology of Human Skin

摘要: The phenotypes and functions of the cells that comprise layers skin immune system are described first. changes occurring in during induction elicitation phases contact hypersensitivity delayed-type summarized as examples cutaneous responses. exposure human to solar UV radiation can result a number effects, many with adverse health outcomes, mechanisms involved each explained turn. Pigmentation develop (immediate pigment darkening delayed tanning), depending on phototype individual. If is greater than minimal erythema dose, sunburn occurs. features photoageing found chronically sun-exposed skin. Skin cancer, most common form cancer fair-skinned subjects, also associated sun exposure, either cumulative or intermittent but intense. two forms nonmelanoma squamous cell basal while third type malignant melanoma, less frequent more dangerous. Solar causes suppression cell-mediated responses, implication this downregulation for effective control tumors infectious diseases considered. Finally, photodermatoses, which represent diverse group conditions linked abnormal responses and/or visible radiation, brief.