Environmental Factors in Cataractogenesis in RCS Rats
作者： Helen H. Hess , J. S. Zigler , T. L. O’Keefe , J. J. Knapka
DOI: 10.1007/978-1-4612-4784-5_9
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摘要: Royal College of Surgeons (RCS) rats have an inherited disease the retinal pigmented epithelium (RPE), which shows a greatly reduced capacity to phagocytize shed terminal portion outer segment rod photoreceptor cell (Mullen & LaVail, 1976). This failure in symbiotic relationship these two cells results accumulation membrane debris at interface between cells, and lack normal nutriture renewal leads death all photoreceptors by about 65 days pink-eyed dystrophies 100 black-eyed (LaVail Battelle, 1975).
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