Altered myocardial states. The stunned and hibernating myocardium.

作者: Robert A. Kloner , Karin Przyklenk , Bharat Patel

DOI: 10.1016/0002-9343(89)90005-3

关键词:

摘要: There are several potential outcomes of myocardial ischemia. When ischemia is severe and prolonged, myocyte cell death occurs there no recovery contractile function these cells. less but still myocytes may remain viable exhibit depressed function, which be a protective mechanism whereby cells attempt to reduce their oxygen demand in the setting reduced supply. The resultant chronic left ventricular dysfunction has been termed "hibernating myocardium." Finally, reversed with coronary artery reperfusion resulting salvage myocytes. However, myocardium demonstrate relatively prolonged transient postischemic dysfunction, situation "stunned concepts stunned reviewed as they apply both during evolving acute infarction, well brief periods that occur angina pectoris, or vasospasm, both. concept hibernating it applies prior after bypass surgery.

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