Sex-specific variation of MRI-based cortical morphometry in adult healthy volunteers: the effect on cognitive functioning.
作者： Benedicto Crespo-Facorro , Roberto Roiz-Santiáñez , Rocío Pérez-Iglesias , Ignacio Mata , Jose Manuel Rodríguez-Sánchez
DOI: 10.1016/J.PNPBP.2011.01.005
关键词:
摘要: Previous investigations have revealed sex-specific differences in brain morphometry. The effect of sex on cortical thickness may be influencing cognitive between sexes. With this exploratory study, we aimed to investigate the MRI-based cerebral cortex morphometry healthy young volunteers and how variability measures might affect functioning men women. 76 (45 31 women) underwent a 1.5 T MR scan 53 them completed comprehensive battery. Overall no gross significant sexes were found thickness, surface area curvature indexes. However, there was group by hemisphere interaction total (F(1,72)=5.02; p=0.03). A greater leftward asymmetry observed males. Only females show associations (IQ executive functioning). In conclusion, our findings do not support notion sexual dimorphism mantle morphology. results also suggest that but
core.ac.uk
elsevier.com
sci-hub.se 参考文章(76)
Mayhew Tm, Henery Cc, The cerebrum and cerebellum of the fixed human brain: efficient and unbiased estimates of volumes and cortical surface areas. Journal of Anatomy. ,vol. 167, pp. 167- 180 ,(1989)
R. Peters, IMAGINGThe Art of Bubble Making Science. ,vol. 282, pp. 432b- 433 ,(1998) , 10.1126/SCIENCE.282.5388.432B
Ruben C. Gur, Bruce I. Turetsky, Mie Matsui, Michelle Yan, Warren Bilker, Paul Hughett, Raquel E. Gur, Sex Differences in Brain Gray and White Matter in Healthy Young Adults: Correlations with Cognitive Performance The Journal of Neuroscience. ,vol. 19, pp. 4065- 4072 ,(1999) , 10.1523/JNEUROSCI.19-10-04065.1999
Joseph J. Ryan, Shane J. Lopez, Wechsler Adult Intelligence Scale-III Understanding Psychological Assessment. pp. 19- 42 ,(2001) , 10.1007/978-1-4615-1185-4_2
Ingrid Agartz, Gaku Okuguwa, Mikael Nordström, Dan Greitz, Vincent Magnotta, Göran Sedvall, Reliability and reproducibility of brain tissue volumetry from segmented MR scans. European Archives of Psychiatry and Clinical Neuroscience. ,vol. 251, pp. 255- 261 ,(2001) , 10.1007/PL00007542
Gregory Harris, Nancy C. Andreasen, Ted Cizadlo, James M. Bailey, H. Jeremy Bockholt, Vincent A. Magnotta, Stephan Arndt, Improving tissue classification in MRI: a three-dimensional multispectral discriminant analysis method with automated training class selection. Journal of Computer Assisted Tomography. ,vol. 23, pp. 144- 154 ,(1999) , 10.1097/00004728-199901000-00030
P. A. Filipek, C. Richelme, D. N. Kennedy, V. S. Caviness, The Young Adult Human Brain: An MRI-based Morphometric Analysis Cerebral Cortex. ,vol. 4, pp. 344- 360 ,(1994) , 10.1093/CERCOR/4.4.344
C. Edward Coffey, Joseph F. Lucke, Judith A. Saxton, Graham Ratcliff, Lori Jo Unitas, Brenda Billig, R. Nick Bryan, Sex differences in brain aging : A quantitative magnetic resonance imaging study JAMA Neurology. ,vol. 55, pp. 169- 179 ,(1998) , 10.1001/ARCHNEUR.55.2.169
Theodore Rabinowicz, Dorothy E. Dean, Jean McDonald-Comber Petetot, Gabrielle M. de Courten-Myers, Gender differences in the human cerebral cortex: more neurons in males; more processes in females. Journal of Child Neurology. ,vol. 14, pp. 98- 107 ,(1999) , 10.1177/088307389901400207
Kiho Im, Jong-Min Lee, Junki Lee, Yong-Wook Shin, In Young Kim, Jun Soo Kwon, Sun I Kim, None, Gender difference analysis of cortical thickness in healthy young adults with surface-based methods. NeuroImage. ,vol. 31, pp. 31- 38 ,(2006) , 10.1016/J.NEUROIMAGE.2005.11.042