The molecular basis of HIV capsid assembly.
作者： Ian M. Jones , Yuko Morikawa
DOI: 10.1002/(SICI)1099-1654(199804/06)8:2<87::AID-RMV220>3.0.CO;2-B
关键词:
摘要: In common with many aspects of the HIV life cycle, assembly virus particle has been subject intense investigation over recent years. Study is facilitated by fact that only a single gene product, Pr55 Gag protein, required for assembly. A combination site directed mutagenesis, biochemical characterisation and structural studies have led to picture overall architecture particle, partial structure Pr55, subdomains involved in oligomerisation. Copyright 1998 John Wiley & Sons, Ltd.
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