Inflammasome priming increases retinal pigment epithelial cell susceptibility to lipofuscin phototoxicity by changing the cell death mechanism from apoptosis to pyroptosis.
作者： Carolina Brandstetter , Joshua Patt , Frank G. Holz , Tim U. Krohne
DOI: 10.1016/J.JPHOTOBIOL.2016.05.018
关键词:
摘要: … In primary human RPE cells and ARPE-19 cells, lipofuscin accumulated following … mW/cm 2 , duration: 3 to 6 h) of lipofuscin-loaded cells and resulted in cell death by apoptosis. Prior …
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