Policy implications of 1080 toxicology in New Zealand.

作者: S. Weaver

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摘要: Sodium monofluoroacetate (1080) is used for large-scale pest control operations in New Zealand to the introduced marsupial brush tailed possum. Wide-scale opposition use of 1080 has grown recent years with development a substantial “anti-1080” lobby. Concerns public health and effects on non-target animals among critics have prompted Environmental Risk Management Authority undertake an official review this pesticide. In anticipation regulatory evaluation peer-reviewed scientific literature was conducted risks associated 1080, order ascertain degree which regulations reflect current knowledge toxicology poison. Key areas concern revealed include evidence that could endocrine disrupting capabilities it relatively slow break down at low temperatures when microbial activity low. These two issues are yet be fully resolved through further research represent significant gaps knowledge. If take full account science they will need acknowledge what known, knowledge, uncertainty. Recommendations targeted fill precaution until such completed, explorations alternative methods either conjunction with, or instead toxin.

参考文章(68)
Frank A. Smith, Dwight E. Gardner, Charles L. Yuile, Ofelia H. de Lopez, Larry L. Hall, Defluorination of fluoroacetate in the rat Life Sciences. ,vol. 20, pp. 1131- 1138 ,(1977) , 10.1016/0024-3205(77)90483-0
Bruce N. Ames, Joyce McCann, Edith Yamasaki, Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test Mutation Research. ,vol. 31, pp. 347- 364 ,(1975) , 10.1016/0165-1161(75)90046-1
S. C. Ogilvie, F. Hetzel, C. T. Eason, Effect of Temperature on the Biodegradation of Sodium Monofluoroacetate (1080) in Water and in Elodea canadensis Bulletin of Environmental Contamination and Toxicology. ,vol. 56, pp. 942- 947 ,(1996) , 10.1007/S001289900136
Christof Schöfl, Julia Börger, Stefanie Lange, Alexander von zur Mühlen, Georg Brabant, Energetic Requirement of Carbachol-Induced Ca2+ Signaling in Single Mouse β-Cells1 Endocrinology. ,vol. 141, pp. 4065- 4071 ,(2000) , 10.1210/ENDO.141.11.7741
H. A. Robertson, R. M. Colbourne, P. Graham, P. J. Miller, R. J. Pierce, Survival of brown kiwi exposed to 1080 poison used for control of brushtail possums in Northland, New Zealand Wildlife Research. ,vol. 26, pp. 209- 214 ,(1999) , 10.1071/WR97001
Chih-Hsien Chi, Kuan-Wen Chen, Shih-Huang Chan, Ming-Ho Wu, Jeng-Jong Huang, Clinical Presentation and Prognostic Factors in Sodium Monofluoroacetate Intoxication Clinical Toxicology. ,vol. 34, pp. 707- 712 ,(1996) , 10.3109/15563659609013833
L.E. Twigg, D.R. King, A.J. Bradley, The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (gray) Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. ,vol. 91, pp. 343- 347 ,(1988) , 10.1016/0742-8413(88)90040-0
Richard D. Wood, Michael Mitchell, John Sgouros, Tomas Lindahl, Human DNA Repair Genes Science. ,vol. 291, pp. 1284- 1289 ,(2001) , 10.1126/SCIENCE.1056154
R. A. PETERS, R. W. WAKELIN, D. E. A. RIVETT, L. C. THOMAS, Fluoroacetate Poisoning: Comparison of Synthetic Fluorocitric Acid with the enzymically synthesized Fluorotricarboxylic Acid Nature. ,vol. 171, pp. 1111- 1112 ,(1953) , 10.1038/1711111A0