Small-field fractionated radiotherapy with or without stereotactic boost for vestibular schwannoma.

摘要: Abstract Purpose : To assess the efficacy and toxicity of small-field fractionated radiotherapy with or without stereotactic boost (SB) for vestibular schwannomas. Methods materials Thirty-nine patients schwannoma were treated irradiation between March 1991 February 1996. Extra-meatal tumor diameters under 30 mm. Thirty-three received followed by SB. Basic dose schedule was 44 Gy in 22 fractions over 5 1/2 weeks plus 4 one session. Six only (40–44 20–22 5–5 36 20 weeks). p>Results Follow-up ranged from 6 to 69 months (median, 24 months). Tumors decreased size 13 cases (33%), unchanged 25 (64%), increased (3%). The actuarial 2-year control rate 97%. Fifteen had useful hearing (Gardner–Robertson class 1–2) testable (class 1–4) before irradiation. rates preservation (free deterioration 1–2 3–5) 78%. any 1–4 5) 96%. No permanent facial trigeminal neuropathy developed after incidences neuropathies 8% 16%, respectively. Conclusions Small-field SB provides excellent short-term local a relatively low incidence complications schwannoma, although further follow-up is necessary evaluate long-term results.