Formulation and Evaluation of In Situ Gelling Systems for Intranasal Administration of Gastrodin

作者: Zheng Cai , Xiangrong Song , Feng Sun , Zhaoxiang Yang , Shixiang Hou

DOI: 10.1208/S12249-011-9678-Y

关键词:

摘要: Gastrodin is the major bioactive constituent of the traditional Chinese drug “Tianma.” It is used in the treatment of some nervous system diseases and can be transported to the brain via …

参考文章(31)
Martin I. Lorin, Irwin D. Mandel, Pureza F. Gaerlan, Quantitative composition of nasal secretions in normal subjects. Journal of Laboratory and Clinical Medicine. ,vol. 80, pp. 275- 281 ,(1972) , 10.5555/URI:PII:0022214372902843
Jiang Xg, Cui Jb, Qiu L, Lu X, Xi Nz, [Studies on octanol-water partition coefficient and nasal drug absorption]. Acta pharmaceutica Sinica. ,vol. 32, pp. 458- ,(1997)
Gang Wei, Hui Xu, Ping Tian Ding, Jun Min Zheng, None, Thermosetting gels with modulated gelation temperature for ophthalmic use: the rheological and gamma scintigraphic studies Journal of Controlled Release. ,vol. 83, pp. 65- 74 ,(2002) , 10.1016/S0168-3659(02)00175-X
Dan Mei, Shirui Mao, Wei Sun, Yanjun Wang, Thomas Kissel, Effect of chitosan structure properties and molecular weight on the intranasal absorption of tetramethylpyrazine phosphate in rats. European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 70, pp. 874- 881 ,(2008) , 10.1016/J.EJPB.2008.06.031
Peter Watts, Alan Smith, PecSys: in situ gelling system for optimised nasal drug delivery Expert Opinion on Drug Delivery. ,vol. 6, pp. 543- 552 ,(2009) , 10.1517/17425240902939135
S CAO, X REN, Q ZHANG, E CHEN, F XU, J CHEN, L LIU, X JIANG, In situ gel based on gellan gum as new carrier for nasal administration of mometasone furoate. International Journal of Pharmaceutics. ,vol. 365, pp. 109- 115 ,(2009) , 10.1016/J.IJPHARM.2008.08.042
R. Mao, J. Tang, B.G. Swanson, Water holding capacity and microstructure of gellan gels Carbohydrate Polymers. ,vol. 46, pp. 365- 371 ,(2001) , 10.1016/S0144-8617(00)00337-4
Dennis Shusterman, Toxicology of nasal irritants. Current Allergy and Asthma Reports. ,vol. 3, pp. 258- 265 ,(2003) , 10.1007/S11882-003-0048-Z
Donella S. Shin, Ann Ojemann Rowe, Robert A. Buchanan, Linda Moretti Ojemann, Wendel L. Nelson, Tian ma, an ancient Chinese herb, offers new options for the treatment of epilepsy and other conditions Epilepsy & Behavior. ,vol. 8, pp. 376- 383 ,(2006) , 10.1016/J.YEBEH.2005.12.009