摘要: The human gut is a huge complex ecosystem where microbiota, nutrients, and host cells interact extensively, process crucial for the homeostasis development with real partnership. various bacterial communities that make up microbiota have many functions including metabolic, barrier effect, trophic functions. Hence, any dysbiosis could negative consequences in terms of health diseases been associated to impairment microbiota. These close relationships between health, disease, led great interest using probiotics (i.e. live micro-organisms), or prebiotics non-digestible substrates) positively modulate prevent treat some diseases. This review focuses on probiotics, their mechanisms action, safety, major benefits. Health benefits remain be proven indications, further studies best strain(s), dose, algorithm administration used are needed. Nevertheless, probiotic seems potential justifies more research.