Hypercycles and compartments

摘要: Abstract The development of the first protocells proceeded by mechanisms which were governed three principles: 1. (1) Self-reproduction molecules identical or similar to modern RNAs was required transmit information from mother daughter molecules. 2. (2) Evolution these improve their phenotypic qualities—stability, error-proneness, and reproduction rate—proceeded in hypercyclically organized systems total content distributed over a number carriers. 3. (3) Compartmentation, insofar as it not already necessary for protection against parasitic infection, became utilization genotypic qualities, i.e. nature macromolecules formed translation products With reśpect different goals, principles are interchangeable. A contrary claim advanced Bresch, Niesert & Harnasch is based on particular model evolution that ignores appearance mutants with differing selective values. In such non-realistic model, error threshold no importance stability wild-type.