作者: Subir Kumar Das , Sukhes Mukherjee , D. M. Vasudevan
DOI: 10.1007/S12291-010-0094-Y
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摘要: Apoptosis plays an important role in cellular homeostasis. In this study we have investigated whether apoptosis is a contributory factor to alcohol induced liver damage. Long term ethanol (1.6 g/kg body weight/day) exposure augmented as reflected by high frequency of positive TUNEL staining nuclei and increased activity caspase-3 -8. Our provides evidence that long-term consumption triggers apoptotic process the liver.