Heritability of thyroid peroxidase autoantibody levels in type 1 diabetes: evidence from discordant twin pairs.

作者: Bin Wang , Mohammed I. Hawa , Frühling V. Rijsdijk , Pamela R. Fain , Stavroula A. Paschou

DOI: 10.1007/S00125-015-3664-Y

关键词:

摘要: Aims/hypothesis The discordance status of (autoimmune) type 1 diabetes within monozygotic twin pairs points to the importance environmental factors. The aim this study was investigate whether events causing influence thyroid autoimmunity.

参考文章(19)
C. B. Shun, K. C. Donaghue, H. Phelan, S. M. Twigg, M. E. Craig, Thyroid autoimmunity in Type 1 diabetes: systematic review and meta-analysis. Diabetic Medicine. ,vol. 31, pp. 126- 135 ,(2014) , 10.1111/DME.12318
M. J. Redondo, L. Yu, M. Hawa, T. Mackenzie, D. A. Pyke, G. S. Eisenbarth, R. D. G. Leslie, Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia. ,vol. 44, pp. 354- 362 ,(2001) , 10.1007/S001250051626
A-G Ziegler, E Bonifacio, Babydiab-Babydiet Study Group, None, Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes. Diabetologia. ,vol. 55, pp. 1937- 1943 ,(2012) , 10.1007/S00125-012-2472-X
C. E. M. De Block, I. H. De Leeuw, J. J. F. Vertommen, R. P. A. Rooman, M. V. L. Du Caju, C. M. Van Campenhout, J. J. Weyler, F. Winnock, J. Van Autreve, F. K. Gorus, , Beta‐cell, thyroid, gastric, adrenal and coeliac autoimmunity and HLA‐DQ types in type 1 diabetes Clinical and Experimental Immunology. ,vol. 126, pp. 236- 241 ,(2001) , 10.1046/J.1365-2249.2001.01668.X
David L. Pauls, Margita Zakarija, J. Maxwell McKenzie, Janice A. Egeland, Complex segregation analysis of antibodies to thyroid peroxidase in old order amish families American Journal of Medical Genetics. ,vol. 47, pp. 375- 379 ,(1993) , 10.1002/AJMG.1320470315
Kyle Kai-How Farh, Alexander Marson, Jiang Zhu, Markus Kleinewietfeld, William J Housley, Samantha Beik, Noam Shoresh, Holly Whitton, Russell JH Ryan, Alexander A Shishkin, Meital Hatan, Marlene J Carrasco-Alfonso, Dita Mayer, C John Luckey, Nikolaos A Patsopoulos, Philip L De Jager, Vijay K Kuchroo, Charles B Epstein, Mark J Daly, David A Hafler, Bradley E Bernstein, None, Genetic and epigenetic fine mapping of causal autoimmune disease variants Nature. ,vol. 518, pp. 337- 343 ,(2015) , 10.1038/NATURE13835
Mark A Atkinson, George S Eisenbarth, Aaron W Michels, Type 1 Diabetes The Lancet. ,vol. 383, pp. 69- 82 ,(2014) , 10.1016/S0140-6736(13)60591-7
S. Genuth, Lowering the Criterion for Impaired Fasting Glucose Is in Order Diabetes Care. ,vol. 26, pp. 3331- 3332 ,(2003) , 10.2337/DIACARE.26.12.3331
Alexander J. MacGregor, Harold Snieder, Alan S. Rigby, Markku Koskenvuo, Jaakko Kaprio, Kimmo Aho, Alan J. Silman, Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins Arthritis & Rheumatism. ,vol. 43, pp. 30- 37 ,(2000) , 10.1002/1529-0131(200001)43:1<30::AID-ANR5>3.0.CO;2-B