Structure-Based Thermodynamic Analysis of HIV-1 Protease Inhibitors†
作者： Jason S. Bardi , Irene Luque , Ernesto Freire
DOI: 10.1021/BI9701742
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摘要: A structural parametrization of the binding and folding energetics previously developed in this laboratory accounts quantitatively for 13 HIV-1 protease inhibitors which high-res...
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A. Fässler, J. Rösel, M. Grüther, M. Tintelnot-Blomley, E. Atteri, G. Bold, M. Lang, Novel pseudosymmetric inhibitors of HIV-1 protease Bioorganic & Medicinal Chemistry Letters. ,vol. 3, pp. 2837- 2842 ,(1993) , 10.1016/S0960-894X(01)80775-7
Suvit Thaisrivongs, Keith D. Watenpaugh, W. Jeffrey Howe, Paul K. Tomich, Lester A. Dolak, Kong-Teck Chong, Che-Shen C. Tomich, Alfredo G. Tomasselli, Steve R. Turner, Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors. Journal of Medicinal Chemistry. ,vol. 38, pp. 3624- 3637 ,(1995) , 10.1021/JM00018A023
Javier Gómez, Ernesto Freire, Thermodynamic Mapping of the Inhibitor Site of the Aspartic Protease Endothiapepsin Journal of Molecular Biology. ,vol. 252, pp. 337- 350 ,(1995) , 10.1006/JMBI.1995.0501
Sergio Cabani, Paolo Gianni, Vincenzo Mollica, Luciano Lepori, Group contributions to the thermodynamic properties of non-ionic organic solutes in dilute aqueous solution Journal of Solution Chemistry. ,vol. 10, pp. 563- 595 ,(1981) , 10.1007/BF00646936
Vincent J. Hilser, Ernesto Freire, Structure-based calculation of the equilibrium folding pathway of proteins. Correlation with hydrogen exchange protection factors. Journal of Molecular Biology. ,vol. 262, pp. 756- 772 ,(1996) , 10.1006/JMBI.1996.0550
Alexander Wlodawer, John W. Erickson, Structure-Based Inhibitors of HIV-1 Protease Annual Review of Biochemistry. ,vol. 62, pp. 543- 585 ,(1993) , 10.1146/ANNUREV.BI.62.070193.002551