Micromirror apparatus for synthesis of arrays of DNA probes

作者: Singh-Gasson Sangeet , Blattner Frederick R , Sussman Michael R , Cerrina Francesco , Green Roland

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摘要: The synthesis of arrays DNA probes sequences, polypeptides, and the like is carried out using a patterning process on an active surface substrate. An image projected onto substrate utilizing former that includes light source provides to micromirror device comprising array electronically addressable micromirrors, each which can be selectively tilted between one at least two positions. Projection optics receives reflected from micromirrors along optical axis precisely images substrate, may used activate first level bases then applied followed by development steps, subsequent exposure different pattern with further repeats until elements dimensional have appropriate base bound thereto. controlled in conjunction synthesizer supplying reagents flow cell containing control sequencing presented coordination provided

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