Synthesis, Optical Properties, and Multiplexed Raman Bio‐Imaging of Surface Roughness‐Controlled Nanobridged Nanogap Particles

摘要: Plasmonic nanostructures are widely studied and used because of their useful size, shape, composition assembled structure-based plasmonic properties. It is, however, highly challenging to precisely design, reproducibly synthesize reliably utilize with enhanced optical Here, we devise a facile synthetic method generate Au surface roughness-controlled nanobridged nanogap particles (Au-RNNPs) ultrasmall (≈1 nm) interior gap tunable roughness in controllable manner. Importantly, found that particle can be associated enhance the electromagnetic field inside gap, stronger nanogap-enhanced Raman scattering (NERS) signals generated from by increasing roughness. The finite-element method-based calculation results support matched well experimental suggest one needs consider nanobridges simultaneously understand control properties this type nanostructures. Finally, potential multiplexed detection imaging RNNPs high-speed, high-resolution bio-imaging Au-RNNPs cells wide-field setup liquid crystal filter demonstrated. Our provide strategies principles designing synthesizing plasmonically show for detecting nanoprobes specific, sensitive