作者: Emily M. Teshome , Veronica S. Oriaro , Pauline E. A. Andango , Andrew M. Prentice , Hans Verhoef
DOI: 10.1186/S12889-018-5097-2
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摘要: The efficacy of home fortification with iron-containing micronutrient powders varies between trials, perhaps in part due to population differences adherence. We aimed assess what extent adherence measured by sachet count or self-reporting forms is agreement electronic device. In addition, we explored how each method assessment (electronic device, count, forms) associated haemoglobin concentration at the end intervention; and baseline factors were as Three hundred thirty-eight rural Kenyan children aged 12-36 months randomly allocated three treatment arms (home two different iron formulations placebo). Home fortificants administered daily parents guardians over a 30 day-intervention period. assessed using an device that stores provides information time day opening container was used store sachets child’s residence. counts. also intervention. Adherence, defined having received least 24 (≥ 80%), during 30-day intervention period attained only 60.6% corresponding values higher when self-report (83.9%; difference: 23.3%, 95% CI: 18.8% 27.8%) (86.3%; 25.7%, 21.0% 30.4%). Among who iron, 10 openings cap storage increase 1.2 g/L (95% 0.0 1.9 g/L). Adherence age parent but not group; age, sex anthropometric indices child; guardian. use self -reporting may lead overestimates fortification. trial registered ClinicalTrials.gov ( NCT02073149 ) on 25 February 2014.