Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies.

作者: Evangeline Tzatzalos , Oscar J. Abilez , Praveen Shukla , Joseph C. Wu

DOI: 10.1016/J.ADDR.2015.09.010

关键词:

摘要: … by the disease phenotype of the iPSC-CM as compared to the … heart rate), the DCM iPSC-CM model recapitulates the DCM … The force of contraction of paced engineered heart tissue …

参考文章(122)
Oscar J. Abilez, Cardiac optogenetics international conference of the ieee engineering in medicine and biology society. ,(2012)
Christine L. Mummery, Jianhua Zhang, Elizabeth S. Ng, David A. Elliott, Andrew G. Elefanty, Timothy J. Kamp, Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes Circulation Research. ,vol. 111, pp. 344- 358 ,(2012) , 10.1161/CIRCRESAHA.110.227512
, Sharon Ann Hunt, William T. Abraham, Marshall H. Chin, Arthur M. Feldman, Gary S. Francis, Theodore G. Ganiats, Mariell Jessup, Marvin A. Konstam, Donna M. Mancini, Keith Michl, John A. Oates, Peter S. Rahko, Marc A. Silver, Lynne Warner Stevenson, Clyde W. Yancy, Elliott M. Antman, Sidney C. Smith, Cynthia D. Adams, Jeffrey L. Anderson, David P. Faxon, Valentin Fuster, Jonathan L. Halperin, Loren F. Hiratzka, Sharon Ann Hunt, Alice K. Jacobs, Rick Nishimura, Joseph P. Ornato, Richard L. Page, Barbara Riegel, ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult Circulation. ,vol. 112, ,(2005) , 10.1161/CIRCULATIONAHA.105.167586
Christopher Paul Adams, Van Vu Brantner, None, Spending on new drug development1. Health Economics. ,vol. 19, pp. 130- 141 ,(2010) , 10.1002/HEC.1454
C L Lawrence, C E Pollard, T G Hammond, J-P Valentin, In vitro models of proarrhythmia British Journal of Pharmacology. ,vol. 154, pp. 1516- 1522 ,(2008) , 10.1038/BJP.2008.195
Wolfram-Hubertus Zimmermann, Ivan Melnychenko, Thomas Eschenhagen, Engineered heart tissue for regeneration of diseased hearts Biomaterials. ,vol. 25, pp. 1639- 1647 ,(2004) , 10.1016/S0142-9612(03)00521-0
Sven Kaese, Sander Verheule, Cardiac electrophysiology in mice: a matter of size. Frontiers in Physiology. ,vol. 3, pp. 345- 345 ,(2012) , 10.3389/FPHYS.2012.00345
Xiulan Yang, Lil Pabon, Charles E. Murry, Engineering Adolescence Maturation of Human Pluripotent Stem Cell–Derived Cardiomyocytes Circulation Research. ,vol. 114, pp. 511- 523 ,(2014) , 10.1161/CIRCRESAHA.114.300558