Directly observed hepatitis C treatment with opioid substitution therapy in community pharmacies: A qualitative study.

作者: Jack Gunn , Peter Higgs

DOI: 10.1016/J.SAPHARM.2019.04.004

关键词:

摘要: Abstract Background The hepatitis C virus (HCV) will only be eliminated through successful engagement with people who inject drugs (PWID), however some of this population experience socioeconomic and individual issues that can lead to poor HCV treatment adherence. A key sub-group (PWID) are those receive opioid substitution therapy (OST). In Australia, OST is most often delivered under direct supervision by a community pharmacist every day or multiple times week. This regular interaction could an ideal opportunity enhance direct-acting antiviral (DAA) adherence directly observed (DOT) the pharmacist. Aim aim study was explore perspectives patients lived understand whether not dispensing DAAs in same way as, simultaneously would benefit treatment. Methods Data collection occurred from June August 2017. Semi-structured interviews were conducted sample PWID living on programs (n = 12) Melbourne, Australia. Interviews voice recorded transcribed verbatim. Interpretive phenomenology guided analysis data. Results Themes reported participants provide insight into suitability DOT include: Adherence non-adherence DAA treatment; Mixed views towards DAAs; Experiences perceptions providers; Perceived stigma pharmacy. Conclusions Community pharmacies offering may effective place for treatment, but likely face significant challenges We suggest positive pharmacist-patient relationship, high adherence, commitment reducing pharmacy necessary intervention effective. Further research needed evaluate expanded-role improving eliminating HCV.

参考文章(29)
Betty B. Chaar, Holly Wang, Carolyn A. Day, Jane R. Hanrahan, Adam R. Winstock, Romano Fois, Factors influencing pharmacy services in opioid substitution treatment. Drug and Alcohol Review. ,vol. 32, pp. 426- 434 ,(2013) , 10.1111/DAR.12032
Carolyn Day, Paul Haber, Martin Weltman, Maryam Alavi, Annie C Balcomb, Nicky Bath, Gregory Dore, Adrian Dunlop, Jason Grebely, Michelle Micallef, Nghi Phung, Carla Treloar, None, Treatment for hepatitis C virus infection among people who inject drugs attending opioid substitution treatment and community health clinics: the ETHOS Study. Addiction. ,vol. 111, pp. 311- 319 ,(2016) , 10.1111/ADD.13197
BB Chaar, Provision of opioid substitution therapy services in Australian pharmacies Australasian Medical Journal. ,vol. 4, pp. 210- 216 ,(2011) , 10.4066/AMJ.2011.706
Mallory O. Johnson, Margaret A. Chesney, Rise B. Goldstein, Robert H. Remien, Sheryl Catz, Cheryl Gore-Felton, Edwin Charlebois, Stephen F. Morin, , Positive provider interactions, adherence self-efficacy, and adherence to antiretroviral medications among HIV-infected adults: A mediation model. Aids Patient Care and Stds. ,vol. 20, pp. 258- 268 ,(2006) , 10.1089/APC.2006.20.258
H. Anglada-Martinez, G. Riu-Viladoms, M. Martin-Conde, M. Rovira-Illamola, J. M. Sotoca-Momblona, C. Codina-Jane, Does mHealth increase adherence to medication? Results of a systematic review International Journal of Clinical Practice. ,vol. 69, pp. 9- 32 ,(2015) , 10.1111/IJCP.12582
Jonathan A Smith, None, Qualitative psychology: a practical guide to research methods Experimental Psychology (formerly "Zeitschrift für Experimentelle Psychologie"). ,vol. 52, pp. 80- 81 ,(2005) , 10.1027/1618-3169.52.1.80
Behzad Hajarizadeh, Jason Grebely, Gregory J. Dore, Epidemiology and natural history of HCV infection Nature Reviews Gastroenterology & Hepatology. ,vol. 10, pp. 553- 562 ,(2013) , 10.1038/NRGASTRO.2013.107
Andrea Krüsi, Evan Wood, Julio Montaner, Thomas Kerr, Social and structural determinants of HAART access and adherence among injection drug users International Journal of Drug Policy. ,vol. 21, pp. 4- 9 ,(2010) , 10.1016/J.DRUGPO.2009.08.003