Improving AIDS Care After Trauma (ImpACT): Pilot Outcomes of a Coping intervention Among HIV-Infected Women with Sexual Trauma in South Africa.

摘要: Improving AIDS Care after Trauma (ImpACT), a coping intervention for HIV-infected women with sexual abuse histories, was evaluated feasibility and potential efficacy in public clinic Cape Town, South Africa. Sixty-four participants were enrolled prior to starting antiretroviral therapy (ART). After completing baseline assessments, randomly assigned standard of care (SoC: three adherence counseling sessions) or ImpACT (SoC plus four individual group sessions). Participants completed assessments at 3 months (after 6 months post-baseline. In exploratory analysis primary outcomes, participants, compared SoC, reported greater reductions avoidance arousal symptoms PTSD increases ART motivation 3 months. Clinically significant decreases overall also demonstrated These effects continued as trends the 6-month assessment, addition social/spiritual coping. secondary high levels non-adherence poor engagement evident 6 months, no differences between study arms. A trauma-focused, culturally-adapted delivered by non-specialist HIV setting is feasible acceptable. Preliminary findings suggest has reduce increase motivation, but more intensive may be needed improve maintain among this population. Trial Registration: ClinicalTrials.gov NCT02223390.