Chromones as therapeutic agents
作者： Mesfin Yimam , Qi Jia , Ji-Fu Zhao , Julie Tseng-Crank
DOI:
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摘要: The present invention describes the identification and isolation of chromones novel chromone compositions from plant sources that exhibit up-regulation adiponectin production by adipocytes normalization virtually hundreds genes related to glucose fatty acid metabolic signaling pathways. are effective in enhancing regulating involved biosynthesis, mitochondrial β-oxidation acids, steroid gluconeogenesis, fat transport, PPARα/RXRα liver xenobiotic metabolism. can be used increase insulin sensitivity, improve tolerance, lower triglyceride levels balance mammals. Included methods for prevention treatment a variety diseases conditions including, but not limited resistance, intolerance, hyperglycemia, syndromes, dyslipidemia, hypertriglyceridemia.
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