Protein Blend Ingestion Following Resistance Exercise Promotes Human Muscle Protein Synthesis

摘要: High-quality proteins such as soy, whey, and casein are all capable of promoting muscle protein synthesis postexercise by activating the mammalian target rapamycin (mTORC1) signaling pathway. We hypothesized that a blend soy dairy would capitalize on unique properties each individual allow for optimal delivery amino acids to prolong fractional synthetic rate (FSR) following resistance exercise (RE). In this double-blind, randomized, clinical trial, 19 young adults were studied before after ingestion ∼19 g (PB) or ∼18 whey (WP) consumed 1 h high-intensity leg RE. examined mixed-muscle FSR stable isotopic methods mTORC1 with western blotting. Muscle biopsies from vastus lateralis collected at rest (before RE) 3 time points during an early (0-2 h) late (2-4 postingestion period. WP resulted in higher earlier amplitude blood branched-chain acid (BCAA) concentrations. PB created lower initial rise BCAA but sustained elevated levels later into recovery (P < 0.05). Postexercise increased equivalently both groups period (WP, 0.078 ± 0.009%; PB, 0.088 0.007%); however, remained only group 0.074 0.010%; 0.087 0.003%) similarly between groups, except no increase S6K1 phosphorylation 5 conclude soy-dairy ingested is prolonging aminoacidemia, signaling, human skeletal effective nutritional supplement.