Adventures in myc-ology
作者： Paul G. Rothberg , Daniel P. Heruth
DOI: 10.1016/S1067-5701(05)80006-3
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摘要: Publisher Summary This chapter discusses the adventures in mycology. Many of now familiar concepts concerning molecular biology cancer are derived from study viral oncology. includes a major contribution to list dominantly acting transforming genes called “oncogenes.” Although oncogenes currently is not dominant theme cancer, an understanding contributions research necessary element any oncogenes. The myc gene discovered avian acute retroviruses, CMII, MC29, MH2, and OK I0. viruses this group cause broad spectrum malignancies vivo , including sarcomas, carcinomas, myelocytomas, also possess ability transform fibroblasts, epithelial cells, bone marrow cells culture. As for all other retroviral oncogenes, ( v-myc ) host cell genome by recombination event between replication competent retrovirus preexisting gene, case cellular c-myc ).
sci-hub.se 参考文章(613)
S Untawale, M Blick, Oncogene expression in adenocarcinomas of the colon and in colon tumor-derived cell lines. Anticancer Research. ,vol. 8, pp. 1- 7 ,(1988)
C C Benz, C K Osborne, G Santos, W M Lee, E Liu, Effects of c-myc overexpression on the growth characteristics of MCF-7 human breast cancer cells. Oncogene. ,vol. 4, pp. 979- 984 ,(1989)
C. Ruppert, D. Goldowitz, W. Wille, Proto-oncogene c-myc is expressed in cerebellar neurons at different developmental stages. The EMBO Journal. ,vol. 5, pp. 1897- 1901 ,(1986) , 10.1002/J.1460-2075.1986.TB04442.X
G.P. Dotto, M.Z. Gilman, M. Maruyama, R.A. Weinberg, c-myc and c-fos expression in differentiating mouse primary keratinocytes. The EMBO Journal. ,vol. 5, pp. 2853- 2857 ,(1986) , 10.1002/J.1460-2075.1986.TB04579.X
Brinster Rl, Quaife Cj, Pinkert Ca, Sandgren Ep, Palmiter Rd, Oncogene-induced liver neoplasia in transgenic mice. Oncogene. ,vol. 4, pp. 715- ,(1989)
D S Askew, J L Cleveland, B C Simmons, R A Ashmun, Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene. ,vol. 6, pp. 1915- 1922 ,(1991)
Brammar Wj, Walker Ra, Varley Jm, Whittaker Jl, Swallow Je, Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis. Oncogene. ,vol. 1, pp. 423- 430 ,(1987)
B. Ripepi, M. Donovan-Peluso, H. Tobon, A. M. Contento, J. Locker, Oncogene amplification in breast cancer. American Journal of Pathology. ,vol. 138, pp. 835- 845 ,(1991)
S. Saule, J. Coll, M. Righi, C. Lagrou, M.B. Raes, D. Stehelin, Two different types of transcription for the myelocytomatosis viruses MH2 and CMII. The EMBO Journal. ,vol. 2, pp. 805- 809 ,(1983) , 10.1002/J.1460-2075.1983.TB01506.X
R. Versteeg, I. A. Noordermeer, M. Krüse-Wolters, D. J. Ruiter, P. I. Schrier, c-myc down-regulates class I HLA expression in human melanomas. The EMBO Journal. ,vol. 7, pp. 1023- 1029 ,(1988) , 10.1002/J.1460-2075.1988.TB02909.X