A Library of Tunable Agarose Carbomer-Based Hydrogels for Tissue Engineering Applications: The Role of Cross-Linkers

作者: Filippo Rossi , Giuseppe Perale , Giuseppe Storti , Maurizio Masi

DOI: 10.1002/APP.34731

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摘要: The role of the crosslinking agents was studied for a series of agarose–carbomer‐based hydrogels, specifically developed for tissue engineering applications, and was quantified using the most typical polycondensation parameter; the ratio between the reacting moieties, ie, hydroxyl (A) and carboxyl (B) groups. Because of the bonds among hydrophilic groups, as A/B ratio was increased, the gel network showed higher compactness and less ability to swell. The role of crosslinkers was also further analyzed using environmental scanning …

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