Dexamethasone receptors and their distribution in the brain of the red tilapia

摘要: Cytosolic extracts of liver and brain showed specific, saturable binding with [3H]dexamethasone: Scatchard plots were linear. Cortisol 11-deoxycortisol acted as competitors, whilst 17α,20α-dihydroxy-4-pregnen-3-one was relatively much less effective. There a four-fold range differences in specific capacity between dissected regions, the order being telencephalon > hypothalamus rhombencephalon optic tectum ≃ (thalamus + tegmentum torus semicircularis) when Nmax calculated terms DNA content. no evidence for any [3;H]dexamethasone membrane fractions.