Uterine artery Doppler flow velocity waveforms in the second trimester for the prediction of preeclampsia and fetal growth retardation.

摘要: Objective To determine the optimal method of measuring uterine artery waveforms with Doppler ultrasound when screening healthy nulliparas for subsequent development preeclampsia and fetal growth retardation (FGR). Methods Color was used to obtain at 19-24 weeks' gestation in 458 nulliparas. In each artery, resistance index (RI), ratio between peak systolic (A) early diastolic (C) blood flow velocities (AC ratio) (a measure notch waveform), placental position were recorded. The predictive values these measurements evaluated pregnancy complications. major end points small gestational age (SGA) infants. Results best test SGA infants placental-side RI or AC above 90th percentile placenta located on left right, highest midline. This identified 51% women had a positive value 29%. detected severe disease requiring delivery before 37 weeks sensitivity 83% specificity 88%. However, results similar if an arbitrary cutoff 0.56 2.05. A normal predicted uncomplicated pregnancy. Conclusions Although abnormal is associated increased risk FGR, do not support its introduction as routine nulliparous women.