The risk of sudden infant death from gastroesophageal reflux
作者： Stephen G. Jolley , Lloyd M. Halpern , William P. Tunell , Dale G. Johnson , Carmen E. Sterling
DOI: 10.1016/0022-3468(91)90012-I
关键词:
摘要: Gastroesophageal reflux (GER) has been a suspected cause of infant deaths and sudden death syndrome (SIDS). We examined our 10-year experience with 499 consecutive infants 6 months age or less who had extended (18 to 24 hours) esophageal pH monitoring performed evaluate for GER. The data extracted from the records included score, pattern GER (type I, II, III), mean duration during sleep (ZMD). All were followed determine occurrence first year life. Of 19 found in series, three classified as SIDS two in-hospital caused by reflux-induced aspiration. five these died prolonged ZMD (greater than 3.8 minutes) received either basic medical (n = 4) no 1) antireflux therapy. Four also type I There was 9.1% (4/44; 95% confidence limits, 2.5% 21.7%) incidence reflux-related treated nonoperatively, compared none (0/83, P .03) same group surgery. higher nonoperatively (3/44, 6.8%) all other (0/265, 0%; .003).(ABSTRACT TRUNCATED AT 250 WORDS)
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