ANTIMALARIAL ACTIVITY OF MEFLOQUINE AND QINGHAOSU
作者： Jing-Bo Jiang , Xing-Bo Guo , Guo-Qiao Li , Yun Cheung Kong , Keith Arnold
DOI: 10.1016/S0140-6736(82)90268-9
关键词:
摘要: Abstract In a chloroquine-resistant Plasmodium falciparum endemic area of Hainan Island, China, 1·0 g oral mefloquine produced radical cure in 47 48 semi-immune patients. A comparison between patients treated with and qinghaosu showed more rapid clearance parasitaemia (68·2±21·4 h vs 103·1±18·0 h) greater inhibition in-vivo trophozoite development. An advantage is the effectiveness single dose, whereas advantages are speed onset action inhibitory effect on parasite maturation.
sci-hub.se 参考文章(10)
C. Teerakiartkamjorn, P. Phintuyothin, E. B. Doberstyn, S. Noeypatimanondh, Single-dose therapy of falciparum malaria with mefloquine or pyrimethamine-sulfadoxine. Bulletin of The World Health Organization. ,vol. 57, pp. 275- 279 ,(1979)
Eliot J. Pearlman, Withoon Thiemanun, Robert S. Kennedy, Craig J. Canfield, Edward B. Doberstyn, Somphong Sudsok, Chemosuppressive field trials in Thailand. IV. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by mefloquine (WR 142,490, A 4-quinolinemethanol). American Journal of Tropical Medicine and Hygiene. ,vol. 29, pp. 1131- 1137 ,(1980) , 10.4269/AJTMH.1980.29.1131
Mark Reacher, John Freeman, CarlosC Campbell, E.Brian Doberstyn, A.David Brandling-Bennett, Drug therapy for Plasmodium falciparum malaria resistant to pyrimethamine-sulfadoxine (Fansidar). A study of alternate regimens in Eastern Thailand, 1980. The Lancet. ,vol. 318, pp. 1066- 1069 ,(1981) , 10.1016/S0140-6736(81)91274-5
EugeneS Hurwitz, David Johnson, CarlosC Campbell, Resistance of Plasmodium falciparum malaria to sulfadoxine-pyrimethamine ('Fansidar') in a refugee camp in Thailand. The Lancet. ,vol. 317, pp. 1068- 1070 ,(1981) , 10.1016/S0140-6736(81)92239-X
A P Hall, E B Doberstyn, C Karnchanachetanee, S Samransamruajkit, B Laixuthai, E J Pearlman, R M Lampe, C F Miller, P Phintuyothin, Sequential treatment with quinine and mefloquine or quinine and pyrimethamine-sulfadoxine for falciparum malaria. BMJ. ,vol. 1, pp. 1626- 1628 ,(1977) , 10.1136/BMJ.1.6077.1626
C. Trenholme, R. Williams, R. Desjardins, H. Frischer, P. Carson, K. Rieckmann, C. Canfield, Mefloquine (WR 142,490) in the treatment of human malaria Science. ,vol. 190, pp. 792- 794 ,(1975) , 10.1126/SCIENCE.1105787
A P Hall, The treatment of malaria. BMJ. ,vol. 1, pp. 323- 328 ,(1976) , 10.1136/BMJ.1.6005.323
R. E. Desjardins, C. L. Pamplin, J. von Bredow, K. G. Barry, C. J. Canfield, Kinetics of a new antimalarial, mefloquine Clinical Pharmacology & Therapeutics. ,vol. 26, pp. 372- 379 ,(1979) , 10.1002/CPT1979263372
Willard T. Haskins, A Simple Qualitative Test for Chloroquine in Urine The American Journal of Tropical Medicine and Hygiene. ,vol. 7, pp. 199- 200 ,(1958) , 10.4269/AJTMH.1958.7.199
WILLIAM CHIN, EDWARD J. COLWELL, DAVID M. BEAR, SANONG KOSAKAL, A COMPARATIVE EVALUATION OF SULFALENE-TRIMETHOPRIM AND SULPHORMETHOXINE-PYRIMETHAMINE AGAINST FALCIPARUM MALARIA IN THAILAND American Journal of Tropical Medicine and Hygiene. ,vol. 22, pp. 308- 312 ,(1973) , 10.4269/AJTMH.1973.22.308