作者: Valentin A. Pavlov , Luis Ulloa , Christine N. Metz
DOI: 10.1016/S1567-7443(10)70027-2
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摘要: Publisher Summary This chapter describes infection and sepsis. Infections are defined as the pathological state following invasion (entrance, growth, proliferation) of microbes (bacteria, viruses, fungi, protozoa) in host organisms. responsible for more deaths worldwide than any other single cause. Despite discovery antibiotics antivirals, well improved sanitary conditions widespread vaccination programs, infections remain a significant health problem. Sepsis, which often follows infection, surgery, and/or trauma, is primary cause death among critically ill patients United States. Sepsis systemic inflammatory response syndrome secondary to suspected or documented infection. The major sites include abdomen, bloodstream respiratory tract. However, not confirmed many with septic symptoms. Originally, sepsis was considered “hypercytokinemia”—that is, associated an exacerbated production cytokines. Today, sepsis-related syndromes understood be considerably complex.