Alternatives to the Neutral Theory

摘要: In the past few years, there has been increasing evidence that much of molecular evolution may not involve neutral alleles. This is almost certainly case from protein5 and be true for silent sites in coding regions as well.9, 14 Should we feel compelled to reject theory certain classes variation, a conspicuous vacuum literature when seek alternative models. The time seems ripe, therefore, begin an exploration non-neutral models see how compatible they are with very observations cast doubt on theory.