作者: Bernard Gaudilliere , Patrick Berna
DOI: 10.1016/S0065-7743(00)35031-X
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摘要: Publisher Summary This chapter discusses new therapeutic entities introduced worldwide in the markets 1999. Among active marketed for human use, biological (NBEs) that were biotechnology-based drugs (mainly recombinant proteins) represented a significant proportion. They innovative approaches to treatment of several important diseases. A total 35 into their first 1999, making it more productive than previous years 1995–1998. The launch considered as priority drugs, which gains over existing patients and medical community ranked particularly high. With 15 launches US maintained top rank terms introductions, followed by Europe Japan with 8 7 respectively. launches, anti-infectives one most groups. An overview different is provided chapter, including abacavir sulfate (antiviral), alitretinoin (anticancer), amprenavir arglabin celecoxib (antiarthritic), cetrorelix, CHF-1301 (antiparkinsonian), colestimide (hypolipidaemic), colforsin daropate hydrochloride, denileukin diftitox others.