A Large‐scale, Hospital‐based Case‐Control Study of Risk Factors of Breast Cancer According to Menopausal Status

摘要: We conducted a large-scale, hospital-based case-control study to evaluate differences and similarities in the risk factors of female breast cancer according menopausal status. This is based on questionnaire survey life style routinely obtained from outpatients who first visited Aichi Cancer Center Hospital between January 1, 1988 December 31, 1992. Among 36,944 outpatients, 1,186 women with detected by histological examination were taken as case group (607 premenopausal 445 postmenopausal women) 23,163 confirmed be free selected control group. New findings reconfirmed follows. 1) The at least one history among subjects' first-degree relatives was relatively high pre- well post-menopausal women. 2) A protective effect physical activity against observed both 3) Dietary decreased cancer. 4) Current smoking drinking elevated 5) Decreasing trends associated intake bean curd, green-yellow vegetables, potato or sweet potato, chicken ham sausage women, while reduction more frequent boiled, broiled and/or raw fish (sashimi). Further will needed clarify age group- birth cohort-specific for young generation Japan.