Premenstrual exacerbation of depression: one process or two?

摘要: Background Premenstrual symptoms occur in the setting of other psychiatric disorders, particularly affective disorders. The nosologic issue whether premenstrual syndrome is an entity distinct from disorders controversial. Method We review association between depression and describe a small series patients (N = 5) with both during after resolution major depression. Results overall symptom severity decreased antidepressant treatment, but this decrease was only significant for dysphoria. In two subjects, cyclical consistent became more apparent treatment depression, possibly because background improved. Conclusion symptoms, including dysphoric changes irritability, can continue despite effective