Minimally Invasive Robotic Kidney Transplantation for Obese Patients Previously Denied Access to Transplantation

作者: J. Oberholzer , P. Giulianotti , K. K. Danielson , M. Spaggiari , L. Bejarano-Pineda

DOI: 10.1111/AJT.12078

关键词:

摘要: Epidemiological data indicate that 20-50% of patients on dialysis for end-stage renal disease (ESRD) are obese (body mass index [BMI] ≥30 kg/m2) (1). Obese with chronic failure have longer wait times until kidney transplantation (2) and inferior patient outcomes (3-7). In the US, example, a BMI 40 kg/m2 (2). Higher BMIs in transplant recipients associated excess risk surgical site infections (SSIs), which negatively impact graft survival (8). Obesity is also comorbidities such as diabetes, although whether obesity increases mortality transplanted remains unclear (8,9). Provider perceptions these risks accompanied by expectation some centers to give time lose weight main reasons why number reluctant list (2,10). Unfortunately, many diabetes hypertension likely secondary their (11) who remain very high rate. The 5-year rate diabetic hypertensive 75 70%, respectively (1). A recent study demonstrated did not present any SSIs had same success normal If procedures could be developed prevent demonstrate successful outcomes, may become less transplantation. Although benefit would still weighed against potential increased from obesity-related comorbidities. prevalence ESRD higher among racial ethnic minority populations, including African-Americans Hispanics, compared Non-Hispanic whites (12-15). These observations suggest developing options help reduce health disparities minorities. We therefore new, minimally invasive, robotic-assisted method using short epigastric incision. This avoids incision infection prone lower quadrants abdomen. We hypothesized priori robotic approach improve patients. Herein, we our experience undergoing minimal at single institution underwent conventional open procedure.

参考文章(25)
Phuong-Thu Pham, Phuong-Anh Pham, Phuong-Chi Pham, Sefali Parikh, Gabriel Danovitch, Evaluation of adult kidney transplant candidates. Seminars in Dialysis. ,vol. 23, pp. 595- 605 ,(2010) , 10.1111/J.1525-139X.2010.00809.X
James J. Thielke, Patricia M. West-Thielke, Heather L. Herren, Umberto Bareato, Thuy Ommert, Vladimir Vidanovic, Sally A. Campbell-Lee, Ivo G. Tzvetanov, Howard N. Sankary, Bruce Kaplan, Enrico Benedetti, Jose Oberholzer, Living donor kidney transplantation across positive crossmatch: the University of Illinois at Chicago experience. Transplantation. ,vol. 87, pp. 268- 273 ,(2009) , 10.1097/TP.0B013E3181919A16
Herwig-Ulf Meier-Kriesche, Mahesh Vaghela, Rama Thambuganipalle, Gary Friedman, Martin Jacobs, Bruce Kaplan, The effect of body mass index on long-term renal allograft survival. Transplantation. ,vol. 68, pp. 1294- 1297 ,(1999) , 10.1097/00007890-199911150-00013
Siddharth Patel, James Cassuto, Mark Orloff, Georgios Tsoulfas, Martin Zand, Randeep Kashyap, Ashok Jain, Adel Bozorgzadeh, Peter Abt, None, Minimizing Morbidity of Organ Donation: Analysis of Factors for Perioperative Complications After Living-Donor Nephrectomy in the United States Transplantation. ,vol. 85, pp. 561- 565 ,(2008) , 10.1097/TP.0B013E3181643CE8
J. L. Gore, P. T. Pham, G. M. Danovitch, A. H. Wilkinson, J. T. Rosenthal, G. S. Lipshutz, J. S. Singer, Obesity and outcome following renal transplantation American Journal of Transplantation. ,vol. 6, pp. 357- 363 ,(2006) , 10.1111/J.1600-6143.2005.01198.X
Raymond J. Lynch, David N. Ranney, Cai Shijie, Dennis S. Lee, Niharika Samala, Michael J. Englesbe, Obesity, surgical site infection, and outcome following renal transplantation. Annals of Surgery. ,vol. 250, pp. 1014- 1020 ,(2009) , 10.1097/SLA.0B013E3181B4EE9A
Veronica Gorodner, Santiago Horgan, Carlos Galvani, Antonio Manzelli, Jose Oberholzer, Howard Sankary, Giuliano Testa, Enrico Benedetti, Routine left robotic-assisted laparoscopic donor nephrectomy is safe and effective regardless of the presence of vascular anomalies. Transplant International. ,vol. 19, pp. 636- 640 ,(2006) , 10.1111/J.1432-2277.2006.00315.X
Eric T. London, Hung S. Ho, Ann M. C. Neuhaus, Bruce M. Wolfe, Steven M. Rudich, Richard V. Perez, Effect of Intravascular Volume Expansion on Renal Function During Prolonged CO2 Pneumoperitoneum Annals of Surgery. ,vol. 231, pp. 195- 201 ,(2000) , 10.1097/00000658-200002000-00007