Microvascular complications in patients with cystic fibrosis-related diabetes (CFRD)

作者: Johanna M.W. van den Berg , Alison M. Morton , Simon W. Kok , Hanno Pijl , Steven P. Conway

DOI: 10.1016/J.JCF.2008.05.008

关键词:

摘要: Abstract Background This study aims to quantitatively and qualitatively assess microvascular complications their risk factors in patients with cystic fibrosis-related diabetes (CFRD) compared those type 1 mellitus (DM1). Methods 79 CFRD were matched DM1 according sex, age duration of insulin therapy. Retinopathy, peripheral neuropathy, nephropathy microalbuminuria the assessed. Risk studied were: smoking, BMI, HbA1c, cholesterol, cholesterol/HDL ratio, diastolic systolic blood pressure. Results Both groups had same number (29%). showed more (21% versus 4.1%; p=0.003), while retinopathy was common (24% 10%; p=0.044). The prevalences neuropathy similar. Patients lower BMI (p Conclusions shown by are similar seen but a prevalence higher microalbuminuria. latter may reflect influence other on renal function.

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