IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions
作者： Kohsuke Kanekura , Xiucui Ma , John T. Murphy , Lihua J. Zhu , Abhinav Diwan
DOI: 10.1126/SCISIGNAL.AAA0341
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摘要: … 5M), suggesting that the increased ROS concentrations were due to ER membrane permeabilization rather than the activation of the PERK-ATF4 pathway. Furthermore, ER stress as …
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Eduard V. Bocharov, Yulia E. Pustovalova, Konstantin V. Pavlov, Pavel E. Volynsky, Marina V. Goncharuk, Yaroslav S. Ermolyuk, Dmitry V. Karpunin, Alexey A. Schulga, Michail P. Kirpichnikov, Roman G. Efremov, Innokenty V. Maslennikov, Alexander S. Arseniev, Unique Dimeric Structure of BNip3 Transmembrane Domain Suggests Membrane Permeabilization as a Cell Death Trigger Journal of Biological Chemistry. ,vol. 282, pp. 16256- 16266 ,(2007) , 10.1074/JBC.M701745200
P Pinton, C Giorgi, R Siviero, E Zecchini, R Rizzuto, Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis Oncogene. ,vol. 27, pp. 6407- 6418 ,(2008) , 10.1038/ONC.2008.308
Heather P. Harding, Yuhong Zhang, Huiquing Zeng, Isabel Novoa, Phoebe D. Lu, Marcella Calfon, Navid Sadri, Chi Yun, Brian Popko, Richard Paules, David F. Stojdl, John C. Bell, Thore Hettmann, Jeffrey M. Leiden, David Ron, An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress Molecular Cell. ,vol. 11, pp. 619- 633 ,(2003) , 10.1016/S1097-2765(03)00105-9
Xiucui Ma, Haiyan Liu, Sarah R. Foyil, Rebecca J. Godar, Carla J. Weinheimer, Joseph A. Hill, Abhinav Diwan, Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury Circulation. ,vol. 125, pp. 3170- 3181 ,(2012) , 10.1161/CIRCULATIONAHA.111.041814
Mark P Mattson, Sic L Chan, Neuronal and glial calcium signaling in Alzheimer's disease. Cell Calcium. ,vol. 34, pp. 385- 397 ,(2003) , 10.1016/S0143-4160(03)00128-3
Xiucui Ma, Rebecca J. Godar, Haiyan Liu, Abhinav Diwan, Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death Autophagy. ,vol. 8, pp. 297- 309 ,(2012) , 10.4161/AUTO.18658
Rajarshi Ghosh, Kathryn L. Lipson, Karen E. Sargent, Arthur M. Mercurio, Joan S. Hunt, David Ron, Fumihiko Urano, Transcriptional Regulation of VEGF-A by the Unfolded Protein Response Pathway PLoS ONE. ,vol. 5, pp. e9575- ,(2010) , 10.1371/JOURNAL.PONE.0009575
Jody Groenendyk, Luis B. Agellon, Marek Michalak, Coping with Endoplasmic Reticulum Stress in the Cardiovascular System Annual Review of Physiology. ,vol. 75, pp. 49- 67 ,(2013) , 10.1146/ANNUREV-PHYSIOL-030212-183707
Dan Han, Alana G. Lerner, Lieselotte Vande Walle, John-Paul Upton, Weihong Xu, Andrew Hagen, Bradley J. Backes, Scott A. Oakes, Feroz R. Papa, IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates Cell. ,vol. 138, pp. 562- 575 ,(2009) , 10.1016/J.CELL.2009.07.017
J. H. Lin, H. Li, D. Yasumura, H. R. Cohen, C. Zhang, B. Panning, K. M. Shokat, M. M. LaVail, P. Walter, IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response Science. ,vol. 318, pp. 944- 949 ,(2007) , 10.1126/SCIENCE.1146361