The Effect of Various Aerosols on the Response of Guinea Pigs to Sulfur Dioxide

摘要: Various types of particulate aerosols (1 to 21 mg/m/sup 3/) were tested for significant synergistic effect with SO/sub 2/. Pulmonary resistance increase after 1-h exposure was the measure irritation. The 2.6 ppM 2/ increased 20%; 10 3/ NaCl, KCl, and NH/sub 4/SCN approx. 2 47, 68 103%, respectively. Potentiation ratio (aerosol/SO/sub alone) 2.4, 3.3, 5.0, respectively, which corresponds solubility in particular salt. Soluble Fe, Mn, V also potentiated 2/, but insoluble salts Fe Mn had no effect. These catalytic worked faster than NaCl possibly because they convert H/sub 2/SO/sub 4/. Fly ash may have a beneficial effect, only statistical manipulations made it significant. Resistance returns normal remains elevated 2/:aerosol (studied 5 h post-exposure at maximum). Both conversion 4/ are responsible effects noted.