Follow-Up Recommendations after Curative Resection of Well-Differentiated Neuroendocrine Tumours: Review of Current Evidence and Clinical Practice.

摘要: The incidence of neuroendocrine neoplasms (NENs) is increasing, especially for patients with early stages and grade 1 tumours. Current evidence also shows increased prevalence, probably reflecting earlier stage diagnosis improvement treatment options. Definition adequate postsurgical follow-up NENs a current challenge. There are limited guidelines, heterogeneity in adherence to those available notable. Unfortunately, the population at greatest risk recurrence has not been defined clearly. Some studies support that pancreatic tumours (PanNETs), factors such as primary tumour (T), stage, (Ki-67), size, lymph node metastases (N) relevance. For bronchial (LungNETs) small intestinal (siNETs), similar have identified. This review summarises supporting rationale behind after curative resection well-differentiated PanNETs, siNETs, LungNETS. Published informing relapse rate, disease-free survival, patterns discussed, together an overview guidelines investigations duration follow-up.