A New and Integral Approach to the Etiopathogenesis and Treatment of Breast Cancer Based upon Its Hydrogen Ion Dynamics

摘要: Despite all efforts, the treatment of breast cancer (BC) cannot be considered to a success story. The advances in surgery, chemotherapy and radiotherapy have not been sufficient at all. Indeed, accumulated experience clearly indicates that new perspectives non-main stream approaches are needed better characterize etiopathogenesis this disease. This contribution deals with how pH-centric anticancer paradigm plays fundamental role reaching more integral understanding etiology, pathogenesis, multifactorial For first time, armamentarium available for different types phases BC is approached here from Unitarian perspective-based upon hydrogen ion dynamics cancer. wide-ranged pH-related molecular, biochemical metabolic model able embrace most fields subfields treatment. single integrated approach allows advancing towards unidirectional, concerted synergistic program Further efforts line likely improve therapeutics each subtype tumor every individual patient phase