The urokinase receptor: a ligand or a receptor? Story of a sociable molecule

作者: P. Ragno

DOI: 10.1007/S00018-005-5428-1

关键词:

摘要: … considered as an endogenous ligand for fMLP receptors [89, 91]. … association with EGF receptor (EGFR) and EGFR phosphorylation. uPA strongly increases integrin-EGFR association …

参考文章(89)
JR Casey, JG Petranka, J Kottra, DE Fleenor, WF Rosse, The structure of the urokinase-type plasminogen activator receptor gene. Blood. ,vol. 84, pp. 1151- 1156 ,(1994) , 10.1182/BLOOD.V84.4.1151.1151
Annapaola Andolfo, William English, Massimo Resnati, Gillian Murphy, Francesco Blasi, Nicolai Sidenius, Metalloproteases cleave the urokinase-type plasminogen activator receptor in the D1-D2 linker region and expose epitopes not present in the intact soluble receptor. Thrombosis and Haemostasis. ,vol. 88, pp. 298- 306 ,(2002) , 10.1055/S-0037-1613202
A. L. Kindzelskii, Wei Xue, Robert F. Todd, Howard R. Petty, Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes. Journal of Immunology. ,vol. 152, pp. 4630- 4640 ,(1994)
A. L. Kindzelskii, Zina O. Laska, Robert F. Todd, Howard R. Petty, Urokinase-type plasminogen activator receptor reversibly dissociates from complement receptor type 3 (alpha M beta 2' CD11b/CD18) during neutrophil polarization. Journal of Immunology. ,vol. 156, pp. 297- 309 ,(1996)
Nathalie Beaufort, Dominique Leduc, Jean-Claude Rousselle, Viktor Magdolen, Thomas Luther, Abdelkader Namane, Michel Chignard, Dominique Pidard, Proteolytic Regulation of the Urokinase Receptor/CD87 on Monocytic Cells by Neutrophil Elastase and Cathepsin G The Journal of Immunology. ,vol. 172, pp. 540- 549 ,(2004) , 10.4049/JIMMUNOL.172.1.540
M. Resnati, M. Guttinger, S. Valcamonica, N. Sidenius, F. Blasi, F. Fazioli, Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect. The EMBO Journal. ,vol. 15, pp. 1572- 1582 ,(1996) , 10.1002/J.1460-2075.1996.TB00502.X
G Høyer-Hansen, E Rønne, H Solberg, N Behrendt, M Ploug, L.R. Lund, V Ellis, K Danø, Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain. Journal of Biological Chemistry. ,vol. 267, pp. 18224- 18229 ,(1992) , 10.1016/S0021-9258(19)37176-5
V Ellis, M F Scully, V V Kakkar, Plasminogen Activation Initiated by Single-chain Urokinase-type Plasminogen Activator Journal of Biological Chemistry. ,vol. 264, pp. 2185- 2188 ,(1989) , 10.1016/S0021-9258(18)94159-1
J Kuiper, M Otter, D C Rijken, T J van Berkel, Characterization of the interaction in vivo of tissue-type plasminogen activator with liver cells. Journal of Biological Chemistry. ,vol. 263, pp. 18220- 18224 ,(1988) , 10.1016/S0021-9258(19)81348-0
Ikuko Mizukami, Robert F. Todd, Wei Xue, Howard R. Petty, Urokinase-Type Plasminogen Activator Receptors Associate with β1 and β3 Integrins of Fibrosarcoma Cells: Dependence on Extracellular Matrix Components Cancer Research. ,vol. 57, pp. 1682- 1689 ,(1997)